CATH Classification

Domain Context

CATH Clusters

Superfamily Beta Polymerase, domain 2
Functional Family Repair DNA polymerase X

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt P42494
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P42494
DPOLX_ASFB7
African swine fever virus BA71V
Repair DNA polymerase X

PDB Structure

PDB 1JQR
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Solution structure of a viral DNA polymerase X and evidence for a mutagenic function.
Showalter, A.K., Byeon, I.J., Su, M.I., Tsai, M.D.
Nat.Struct.Biol.