CATH Classification

Domain Context

CATH Clusters

Superfamily 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Functional Family 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

Enzyme Information

4.6.1.12
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase.
based on mapping to UniProt P44815
2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = 2-C-methyl- D-erythritol 2,4-cyclodiphosphate + CMP.
-!- Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis.

UniProtKB Entries (1)

P44815
ISPF_HAEIN
Haemophilus influenzae Rd KW20
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

PDB Structure

PDB 1JN1
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of 2C-methyl-D-erythrol-2,4-cyclodiphosphate synthase from Haemophilus influenzae: activation by conformational transition.
Lehmann, C., Lim, K., Toedt, J., Krajewski, W., Howard, A., Eisenstein, E., Herzberg, O.
Proteins