CATH Classification

Domain Context

CATH Clusters

Superfamily Antithrombin, subunit I, domain 2
Functional Family heparin cofactor 2 isoform X1

Enzyme Information

UniProtKB Entries (1)

P05546
HEP2_HUMAN
Homo sapiens
Heparin cofactor 2

PDB Structure

PDB 1JMO
External Links
Method X-RAY DIFFRACTION
Organism Cricetulus
Primary Citation
Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism.
Baglin, T.P., Carrell, R.W., Church, F.C., Esmon, C.T., Huntington, J.A.
Proc.Natl.Acad.Sci.USA