CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.10490 | Glucose-6-phosphate isomerase like protein; domain 1 |
Domain Context
CATH Clusters
| Superfamily | Glucose-6-phosphate isomerase like protein; domain 1 |
| Functional Family |
Enzyme Information
| 5.3.1.27 |
6-phospho-3-hexuloisomerase.
based on mapping to UniProt Q58644
D-arabino-hex-3-ulose 6-phosphate = D-fructose 6-phosphate.
-!- This enzyme, along with EC 4.1.2.43, plays a key role in the ribulose-monophosphate cycle of formaldehyde fixation, which is present in many microorganisms that are capable of utilizing C1-compounds. -!- The hyperthermophilic and anaerobic archaeon Pyrococcus horikoshii OT3 constitutively produces a bifunctional enzyme that sequentially catalyzes the reactions of EC 4.1.2.43 and this enzyme.
|
UniProtKB Entries (1)
| Q58644 |
PHI_METJA
Methanocaldococcus jannaschii DSM 2661
3-hexulose-6-phosphate isomerase
|
PDB Structure
| PDB | 1JEO |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of MJ1247 protein from M. jannaschii at 2.0 A resolution infers a molecular function of 3-hexulose-6-phosphate isomerase.
Structure
|