CATH Classification

Domain Context

CATH Clusters

Superfamily D-amino Acid Aminotransferase, subunit A, domain 2
Functional Family Branched-chain-amino-acid aminotransferase

Enzyme Information

2.6.1.42
Branched-chain-amino-acid transaminase.
based on mapping to UniProt P0AB80
L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.
-!- Also acts on L-isoleucine and L-valine. -!- Different from EC 2.6.1.66.

UniProtKB Entries (1)

P0AB80
ILVE_ECOLI
Escherichia coli K-12
Branched-chain-amino-acid aminotransferase

PDB Structure

PDB 1IYD
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structures of branched-chain amino Acid aminotransferase complexed with glutamate and glutarate: true reaction intermediate and double substrate recognition of the enzyme.
Goto, M., Miyahara, I., Hayashi, H., Kagamiyama, H., Hirotsu, K.
Biochemistry