CATH Classification

Domain Context

CATH Clusters

Superfamily Butyryl-CoA Dehydrogenase, subunit A, domain 3
Functional Family isovaleryl-CoA dehydrogenase, mitochondrial

Enzyme Information

1.3.8.4
Isovaleryl-CoA dehydrogenase.
based on mapping to UniProt P26440
Isovaleryl-CoA + electron-transfer flavoprotein = 3-methylcrotonyl-CoA + reduced electron-transfer flavoprotein.
-!- Pentanoate can act as donor. -!- Formerly EC 1.3.99.10.

UniProtKB Entries (1)

P26440
IVD_HUMAN
Homo sapiens
Isovaleryl-CoA dehydrogenase, mitochondrial

PDB Structure

PDB 1IVH
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of human isovaleryl-CoA dehydrogenase at 2.6 A resolution: structural basis for substrate specificity,.
Tiffany, K.A., Roberts, D.L., Wang, M., Paschke, R., Mohsen, A.W., Vockley, J., Kim, J.J.
Biochemistry