CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.970
Functional Family Transketolase 1, thiamin-binding protein

Enzyme Information

2.2.1.1
Transketolase.
based on mapping to UniProt Q7SIC9
Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate.
-!- Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO(2) and R-CHOH-CO-CH(2)OH. -!- The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor.

UniProtKB Entries (1)

Q7SIC9
TKTC_MAIZE
Zea mays
Transketolase, chloroplastic

PDB Structure

PDB 1ITZ
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure and properties of an engineered transketolase from maize
Gerhardt, S., Echt, S., Busch, M., Freigang, J., Auerbach, G., Bader, G., Martin, W.F., Bacher, A., Huber, R., Fischer, M.
PLANT PHYSIOL.