CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonuclease hii. Domain 2
Functional Family Ribonuclease

Enzyme Information

3.1.26.4
Ribonuclease H.
based on mapping to UniProt O74035
Endonucleolytic cleavage to 5'-phosphomonoester.
-!- Acts on RNA-DNA hybrids.

UniProtKB Entries (1)

O74035
RNH2_THEKO
Thermococcus kodakarensis KOD1
Ribonuclease HII

PDB Structure

PDB 1IO2
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Catalytic center of an archaeal type 2 ribonuclease H as revealed by X-ray crystallographic and mutational analyses.
Muroya, A., Tsuchiya, D., Ishikawa, M., Haruki, M., Morikawa, M., Kanaya, S., Morikawa, K.
Protein Sci.