CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Malate dehydrogenase

Enzyme Information

1.1.1.37
Malate dehydrogenase.
based on mapping to UniProt P61889
(S)-malate + NAD(+) = oxaloacetate + NADH.
-!- Also oxidizes some other 2-hydroxydicarboxylic acids.

UniProtKB Entries (1)

P61889
MDH_ECOLI
Escherichia coli K-12
Malate dehydrogenase

PDB Structure

PDB 1IB6
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural Analyses of a Malate Dehydrogenase with a Variable Active Site
Bell, J.K., Yennawar, H.P., Wright, S.K., Thompson, J.R., Viola, R.E., Banaszak, L.J.
J.Biol.Chem.