CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family UDP-glucose 4-epimerase

Enzyme Information

5.1.3.7
UDP-N-acetylglucosamine 4-epimerase.
based on mapping to UniProt Q14376
UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-galactosamine.
5.1.3.2
UDP-glucose 4-epimerase.
based on mapping to UniProt Q14376
UDP-alpha-D-glucose = UDP-alpha-D-galactose.
-!- Also acts on UDP-2-deoxyglucose.

UniProtKB Entries (1)

Q14376
GALE_HUMAN
Homo sapiens
UDP-glucose 4-epimerase

PDB Structure

PDB 1I3N
External Links
Method X-RAY DIFFRACTION
Organism Pichia
Primary Citation
Molecular basis for severe epimerase deficiency galactosemia. X-ray structure of the human V94m-substituted UDP-galactose 4-epimerase.
Thoden, J.B., Wohlers, T.M., Fridovich-Keil, J.L., Holden, H.M.
J.Biol.Chem.