CATH Classification

Domain Context

CATH Clusters

Superfamily DD-peptidase/beta-lactamase superfamily
Functional Family

Enzyme Information

3.5.2.6
Beta-lactamase.
based on mapping to UniProt P00808
A beta-lactam + H(2)O = a substituted beta-amino acid.
-!- Zinc is only requires in class-B enzymes. -!- A group of enzymes of varying specificity hydrolyzing beta-lactams; some act more rapidly on penicillins, some more rapidly on cephalosporins. -!- Formerly EC 3.5.2.8.

UniProtKB Entries (1)

P00808
BLAC_BACLI
Bacillus licheniformis
Beta-lactamase

PDB Structure

PDB 1I2S
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structures of the Bacillus licheniformis BS3 class A beta-lactamase and of the acyl-enzyme adduct formed with cefoxitin
Fonze, E., Vanhove, M., Dive, G., Sauvage, E., Frere, J.M., Charlier, P.
Biochemistry