CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | 3-oxoacyl-[acyl-carrier-protein] reductase FabG |
Enzyme Information
| 1.1.1.100 |
3-oxoacyl-[acyl-carrier-protein] reductase.
based on mapping to UniProt P0AEK2
(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP(+) = 3-oxoacyl-[acyl- carrier-protein] + NADPH.
-!- Exhibits a marked preference for [acyl-carrier-protein] derivatives over CoA derivatives as substrates.
|
UniProtKB Entries (1)
| P0AEK2 |
FABG_ECOLI
Escherichia coli K-12
3-oxoacyl-[acyl-carrier-protein] reductase FabG
|
PDB Structure
| PDB | 1I01 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure of beta-ketoacyl-[acyl carrier protein] reductase from Escherichia coli: negative cooperativity and its structural basis.
Biochemistry
|
