CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | Short-chain dehydrogenase reductase |
Enzyme Information
| 1.1.1.51 |
3(or 17)-beta-hydroxysteroid dehydrogenase.
based on mapping to UniProt P19871
Testosterone + NAD(P)(+) = androst-4-ene-3,17-dione + NAD(P)H.
-!- Also acts on other 3-beta- or 17-beta-hydroxysteroids (cf. EC 1.1.1.209).
|
UniProtKB Entries (1)
| P19871 |
3BHD_COMTE
Comamonas testosteroni
3-beta-hydroxysteroid dehydrogenase
|
PDB Structure
| PDB | 1HXH |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure of Bacterial 3beta/17beta-Hydroxysteroid Dehydrogenase at 1.2 A Resolution: A Model for
Multiple Steroid Recognition
Biochemistry
|