CATH Classification

Domain Context

CATH Clusters

Superfamily Lumazine/riboflavin synthase
Functional Family 6,7-dimethyl-8-ribityllumazine synthase

Enzyme Information

2.5.1.78
6,7-dimethyl-8-ribityllumazine synthase.
based on mapping to UniProt O66529
1-deoxy-L-glycero-tetrulose 4-phosphate + 5-amino-6- (D-ribitylamino)uracil = 6,7-dimethyl-8-(D-ribityl)lumazine + 2 H(2)O + phosphate.
-!- Involved in riboflavin biosynthesis.

UniProtKB Entries (1)

O66529
RISB_AQUAE
Aquifex aeolicus VF5
6,7-dimethyl-8-ribityllumazine synthase

PDB Structure

PDB 1HQK
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
X-ray structure analysis and crystallographic refinement of lumazine synthase from the hyperthermophile Aquifex aeolicus at 1.6 A resolution: determinants of thermostability revealed from structural comparisons.
Zhang, X., Meining, W., Fischer, M., Bacher, A., Ladenstein, R.
J.Mol.Biol.