CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside diphosphate kinase-like domain
Functional Family Nucleoside diphosphate kinase

Enzyme Information

2.7.4.6
Nucleoside-diphosphate kinase.
based on mapping to UniProt P22887
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
-!- Many nucleoside diphosphates can act as acceptors. -!- Many ribo- and deoxyribonucleoside triphosphates can act as donors.

UniProtKB Entries (1)

P22887
NDKC_DICDI
Dictyostelium discoideum
Nucleoside diphosphate kinase, cytosolic

PDB Structure

PDB 1HLW
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Chemical rescue of phosphoryl transfer in a cavity mutant: a cautionary tale for site-directed mutagenesis.
Admiraal, S.J., Meyer, P., Schneider, B., Deville-Bonne, D., Janin, J., Herschlag, D.
Biochemistry