CATH Classification

Domain Context

CATH Clusters

Superfamily Macrophage Migration Inhibitory Factor
Functional Family

Enzyme Information

5.3.2.1
Phenylpyruvate tautomerase.
based on mapping to UniProt P81529
Keto-phenylpyruvate = enol-phenylpyruvate.
-!- Also acts on other arylpyruvates.
5.3.3.12
L-dopachrome isomerase.
based on mapping to UniProt P81529
L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.
-!- Stereospecific for L-dopachrome (5,6-dioxo-2,3-5,6-tetrahydroindole- 2-carboxylate). -!- Dopachrome methyl ester is a substrate, but dopaminochrome (2,3- dihydroxyindolyl-5,6-quinone) is not (see also EC 4.1.1.84).

UniProtKB Entries (1)

P81529
MIFH_TRISP
Trichinella spiralis
Macrophage migration inhibitory factor homolog

PDB Structure

PDB 1HFO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Macrophage Migration Inhibitory Factor of the Parasitic Nematode Trichinella Spiralis
Tan, T.H., Edgerton, S.A., Kumari, R., Mcalister, M.S., Rowe, S.M., Nagl, S., Pearl, L.H., Selkirk, M.E., Bianco, A.E., Totty, N.F., Engwerda, C., Gray, C.A., Meyer, D.J.
Biochem.J.