CATH Domain 1he4A00

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.720	NAD(P)-binding Rossmann-like Domain

Domain Context

CATH Clusters

Superfamily	NAD(P)-binding Rossmann-like Domain
Functional Family	flavin reductase (NADPH)

Enzyme Information

1.5.1.30	Flavin reductase (NADPH). based on mapping to UniProt P30043 Reduced riboflavin + NADP(+) = riboflavin + NADPH. -!- The enzyme from Entamoeba histolytica reduces riboflavin and galactoflavin, and, more slowly, FMN and FAD. -!- NADH is oxidized more slowly than NADPH. -!- Formerly EC 1.6.8.2.
1.3.1.24	Biliverdin reductase. based on mapping to UniProt P30043 Bilirubin + NAD(P)(+) = biliverdin + NAD(P)H.

UniProtKB Entries (1)

BLVRB_HUMAN

Homo sapiens

Flavin reductase (NADPH)

PDB Structure

PDB	1HE4
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure of Human Biliverdin Ix Beta Reductase, an Early Fetal Bilirubin Ix Producing Enzyme Pereira, P.J.B., Macedo-Ribeiro, S., Parraga, A., Perez-Luque, R., Cunningham, O., Darcy, K., Mantle, T.J., Coll, M. Nat.Struct.Biol.