CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family flavin reductase (NADPH)

Enzyme Information

1.5.1.30
Flavin reductase (NADPH).
based on mapping to UniProt P30043
Reduced riboflavin + NADP(+) = riboflavin + NADPH.
-!- The enzyme from Entamoeba histolytica reduces riboflavin and galactoflavin, and, more slowly, FMN and FAD. -!- NADH is oxidized more slowly than NADPH. -!- Formerly EC 1.6.8.2.
1.3.1.24
Biliverdin reductase.
based on mapping to UniProt P30043
Bilirubin + NAD(P)(+) = biliverdin + NAD(P)H.

UniProtKB Entries (1)

P30043
BLVRB_HUMAN
Homo sapiens
Flavin reductase (NADPH)

PDB Structure

PDB 1HE3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of Human Biliverdin Ix Beta Reductase, an Early Fetal Bilirubin Ix Producing Enzyme
Pereira, P.J.B., Macedo-Ribeiro, S., Parraga, A., Perez-Luque, R., Cunningham, O., Darcy, K., Mantle, T.J., Coll, M.
Nat.Struct.Biol.