CATH Classification

Domain Context

CATH Clusters

Superfamily Bira Bifunctional Protein; Domain 2
Functional Family Proline--tRNA ligase

Enzyme Information

6.1.1.15
Proline--tRNA ligase.
based on mapping to UniProt Q5SM28
ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro).

UniProtKB Entries (1)

Q5SM28
SYP_THET8
Thermus thermophilus HB8
Proline--tRNA ligase

PDB Structure

PDB 1H4Q
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A Succession of Substrate Induced Conformational Changes Ensures the Amino Acid Specificity of Thermus Thermophilus Prolyl-tRNA Synthetase: Comparison with Histidyl-tRNA Synthetase
Yaremchuk, A., Tukalo, M., Grotli, M., Cusack, S.
J.Mol.Biol.