CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.740
Functional Family

Enzyme Information

1.17.1.9
Formate dehydrogenase.
based on mapping to UniProt Q934F5
Formate + NAD(+) = CO(2) + NADH.
-!- The enzyme from most aerobic organisms is devoid of redox-active centers but that from the proteobacterium Methylosinus trichosporium contains iron-sulfur centers, flavin and a molybdenum center. -!- Together with EC 1.12.1.2, forms a system previously known as formate hydrogenlyase. -!- Formerly EC 1.2.1.2.

UniProtKB Entries (2)

Q8GC87
FDHB_DESGG
Desulfovibrio gigas DSM 1382 = ATCC 19364
Formate dehydrogenase subunit beta
Q934F5
FDHA_DESGI
Desulfovibrio gigas
Formate dehydrogenase subunit alpha

PDB Structure

PDB 1H0H
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Gene Sequence and the 1.8 A Crystal Structure of the Tungsten-Containing Formate Dehydrogenase from Desulfovibrio Gigas
Raaijmakers, H.C.A., Macieira, S., Dias, J., Teixeira, S., Bursakov, S., Huber, R., Moura, J., Moura, I., Romao, M.
Structure