CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
Functional Family

Enzyme Information

2.4.2.18
Anthranilate phosphoribosyltransferase.
based on mapping to UniProt P50384
N-(5-phospho-D-ribosyl)-anthranilate + diphosphate = anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 4.1.1.48, EC 4.1.3.27, EC 4.2.1.20 and EC 5.3.1.24).

UniProtKB Entries (1)

P50384
TRPD_SACS2
Saccharolobus solfataricus P2
Anthranilate phosphoribosyltransferase

PDB Structure

PDB 1GXB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Analysis of Two Enzymes Catalysing Reverse Metabolic Reactions Implies Common Ancestry
Mayans, O., Ivens, A., Nissen, L.J., Kirschner, K., Wilmanns, M.
Embo J.