CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.2140 | Arylamine N-acetyltransferase fold |
|
3.30.2140.10 | Arylamine N-acetyltransferase |
Domain Context
CATH Clusters
| Superfamily | Arylamine N-acetyltransferase |
| Functional Family |
Enzyme Information
| 2.3.1.5 |
Arylamine N-acetyltransferase.
based on mapping to UniProt O86309
Acetyl-CoA + an arylamine = CoA + an N-acetylarylamine.
-!- Wide specificity for aromatic amines, including serotonin; also catalyzes acetyl-transfer between arylamines without CoA.
|
UniProtKB Entries (1)
| O86309 |
NAT_MYCSM
Mycolicibacterium smegmatis
Arylamine N-acetyltransferase
|
PDB Structure
| PDB | 1GX3 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The Structure of Arylamine N-Acetyltransferase from Mycobacterium Smegmatis-an Enzyme which Inactivates the Anti-Tubercular Drug, Isoniazid
J.Mol.Biol.
|