CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.260 | 434 Repressor (Amino-terminal Domain) |
|
1.10.260.40 | lambda repressor-like DNA-binding domains |
Domain Context
CATH Clusters
| Superfamily | lambda repressor-like DNA-binding domains |
| Functional Family | POU domain protein |
Enzyme Information
UniProtKB Entries (2)
| P48432 |
SOX2_MOUSE
Mus musculus
Transcription factor SOX-2
|
| P14859 |
PO2F1_HUMAN
Homo sapiens
POU domain, class 2, transcription factor 1
|
PDB Structure
| PDB | 1GT0 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of a POU/Hmg/DNA Ternary Complex Suggests Differential Assembly of Oct4 and Sox2 on Two Enhancers
Genes Dev.
|