CATH Classification

Domain Context

CATH Clusters

Superfamily Collagenase (Catalytic Domain)
Functional Family

Enzyme Information

3.4.24.20
Peptidyl-Lys metalloendopeptidase.
based on mapping to UniProt P81054
Preferential cleavage in proteins: -Xaa-|-Lys- (in which Xaa may be Pro).
-!- From the honey fungus Armillaria mellea. -!- A similar specificity is shown by Myxobacter sp. AL-1 proteinase II (endoproteinase Lys-C). -!- Formerly EC 3.4.99.30 and EC 3.4.99.32.

UniProtKB Entries (1)

P81054
PLMP_GRIFR
Grifola frondosa
Peptidyl-Lys metalloendopeptidase

PDB Structure

PDB 1GE6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of a new 'aspzincin' metalloendopeptidase from Grifola frondosa: implications for the catalytic mechanism and substrate specificity based on several different crystal forms.
Hori, T., Kumasaka, T., Yamamoto, M., Nonaka, N., Tanaka, N., Hashimoto, Y., Ueki, U., Takio, K.
Acta Crystallogr.,Sect.D