CATH Classification

Domain Context

CATH Clusters

Superfamily 1.50.10.10
Functional Family Glucoamylase

Enzyme Information

3.2.1.3
Glucan 1,4-alpha-glucosidase.
based on mapping to UniProt P69327
Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D- glucose.
-!- Most forms of the enzyme can rapidly hydrolyze 1,6-alpha-D-glucosidic bonds when the next bond in the sequence is 1,4, and some preparations of this enzyme hydrolyze 1,6- and 1,3-alpha-D-glucosidic bonds in other polysaccharides. -!- This entry covers all such enzymes acting on polysaccharides more rapidly than on oligosaccharides. -!- EC 3.2.1.20 from mammalian intestine can catalyze similar reactions.

UniProtKB Entries (1)

P69327
AMYG_ASPAW
Aspergillus awamori
Glucoamylase

PDB Structure

PDB 1GAH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystallographic complexes of glucoamylase with maltooligosaccharide analogs: relationship of stereochemical distortions at the nonreducing end to the catalytic mechanism.
Aleshin, A.E., Stoffer, B., Firsov, L.M., Svensson, B., Honzatko, R.B.
Biochemistry