CATH Classification

Domain Context

CATH Clusters

Superfamily Toll/interleukin-1 receptor homology (TIR) domain
Functional Family Toll-like receptor 2

Enzyme Information

UniProtKB Entries (1)

Q15399
TLR1_HUMAN
Homo sapiens
Toll-like receptor 1

PDB Structure

PDB 1FYV
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for signal transduction by the Toll/interleukin-1 receptor domains.
Xu, Y., Tao, X., Shen, B., Horng, T., Medzhitov, R., Manley, J.L., Tong, L.
Nature