CATH Domain 1ft4B02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.10	Ribbon
	2.10.50	Tumor Necrosis Factor Receptor, subunit A; domain 2
	2.10.50.10	Tumor Necrosis Factor Receptor, subunit A, domain 2

Domain Context

CATH Clusters

Superfamily	Tumor Necrosis Factor Receptor, subunit A, domain 2
Functional Family	Tumor necrosis factor receptor superfamily member 1A

Enzyme Information

UniProtKB Entries (1)

TNR1A_HUMAN

Homo sapiens

Tumor necrosis factor receptor superfamily member 1A

PDB Structure

PDB	1FT4
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Photochemically enhanced binding of small molecules to the tumor necrosis factor receptor-1 inhibits the binding of TNF-alpha. Carter, P.H., Scherle, P.A., Muckelbauer, J.K., Voss, M.E., Liu, R.Q., Thompson, L.A., Tebben, A.J., Solomon, K.A., Lo, Y.C., Li, Z., Strzemienski, P., Yang, G., Falahatpisheh, N., Xu, M., Wu, Z., Farrow, N.A., Ramnarayan, K., Wang, J., Rideout, D., Yalamoori, V., Domaille, P., Underwood, D.J., Trzaskos, J.M., Friedman, S.M., Newton, R.C., Decicco, C.P., Muckelbauer, J.A. Proc.Natl.Acad.Sci.USA