CATH Classification

Domain Context

CATH Clusters

Superfamily Dbl homology (DH) domain
Functional Family T cell lymphoma invasion and metastasis 1

Enzyme Information

UniProtKB Entries (2)

Q60610
TIAM1_MOUSE
Mus musculus
T-lymphoma invasion and metastasis-inducing protein 1
P63000
RAC1_HUMAN
Homo sapiens
Ras-related C3 botulinum toxin substrate 1

PDB Structure

PDB 1FOE
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1.
Worthylake, D.K., Rossman, K.L., Sondek, J.
Nature