CATH Classification

Domain Context

CATH Clusters

Superfamily DNA Methylase, subunit A, domain 2
Functional Family

Enzyme Information

2.1.1.37
DNA (cytosine-5-)-methyltransferase.
based on mapping to UniProt P05102
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
-!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/ -!- Formerly EC 2.1.1.73.

UniProtKB Entries (1)

P05102
MTH1_HAEPH
Haemophilus parahaemolyticus
Modification methylase HhaI

PDB Structure

PDB 1FJX
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Functional roles of the conserved threonine 250 in the target recognition domain of HhaI DNA methyltransferase.
Vilkaitis, G., Dong, A., Weinhold, E., Cheng, X., Klimasauskas, S.
J.Biol.Chem.