CATH Classification

Domain Context

CATH Clusters

Superfamily 3.60.21.10
Functional Family Serine/threonine-protein phosphatase

Enzyme Information

3.1.3.16
Protein-serine/threonine phosphatase.
based on mapping to UniProt P62139
[a protein]-serine/threonine phosphate + H(2)O = [a protein]- serine/threonine + phosphate.
-!- A group of enzymes removing the serine- or threonine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase (cf. EC 3.1.3.48). -!- The spleen enzyme also acts on phenolic phosphates and phosphamides (cf. EC 3.9.1.1).

UniProtKB Entries (1)

P62139
PP1A_RABIT
Oryctolagus cuniculus
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

PDB Structure

PDB 1FJM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1.
Goldberg, J., Huang, H.B., Kwon, Y.G., Greengard, P., Nairn, A.C., Kuriyan, J.
Nature