CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.10010 | Type-2 restriction enzyme NgoMIV |
Domain Context
CATH Clusters
| Superfamily | Type-2 restriction enzyme NgoMIV |
| Functional Family |
Enzyme Information
| 3.1.21.4 |
Type II site-specific deoxyribonuclease.
based on mapping to UniProt P31032
Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
-!- Large group of enzymes which recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition site. -!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
|
UniProtKB Entries (1)
| P31032 |
T2M4_NEIGO
Neisseria gonorrhoeae
Type-2 restriction enzyme NgoMIV
|
PDB Structure
| PDB | 1FIU |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure of the tetrameric restriction endonuclease NgoMIV in complex with cleaved DNA.
Nat.Struct.Biol.
|