CATH Classification

Domain Context

CATH Clusters

Superfamily GHMP kinase, C-terminal domain
Functional Family Diphosphomevalonate decarboxylase

Enzyme Information

4.1.1.33
Diphosphomevalonate decarboxylase.
based on mapping to UniProt P32377
ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl diphosphate + CO(2).

UniProtKB Entries (1)

P32377
MVD1_YEAST
Saccharomyces cerevisiae S288C
Diphosphomevalonate decarboxylase

PDB Structure

PDB 1FI4
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural genomics of enzymes involved in sterol/isoprenoid biosynthesis.
Bonanno, J.B., Edo, C., Eswar, N., Pieper, U., Romanowski, M.J., Ilyin, V., Gerchman, S.E., Kycia, H., Studier, F.W., Sali, A., Burley, S.K.
Proc.Natl.Acad.Sci.USA