CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.60.20
Functional Family B-Raf proto-oncogene serine/threonine-protein kinase

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P04049
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P04049
RAF1_HUMAN
Homo sapiens
RAF proto-oncogene serine/threonine-protein kinase

PDB Structure

PDB 1FAQ
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site.
Mott, H.R., Carpenter, J.W., Zhong, S., Ghosh, S., Bell, R.M., Campbell, S.L.
Proc.Natl.Acad.Sci.USA