CATH Classification

Domain Context

CATH Clusters

Superfamily 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1
Functional Family Lactoylglutathione lyase

Enzyme Information

4.4.1.5
Lactoylglutathione lyase.
based on mapping to UniProt P0AC81
(R)-S-lactoylglutathione = glutathione + methylglyoxal.
-!- Also acts on 3-phosphoglycerol-glutathione.

UniProtKB Entries (1)

P0AC81
LGUL_ECOLI
Escherichia coli K-12
Lactoylglutathione lyase

PDB Structure

PDB 1FA6
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Determination of the structure of Escherichia coli glyoxalase I suggests a structural basis for differential metal activation.
He, M.M., Clugston, S.L., Honek, J.F., Matthews, B.W.
Biochemistry