CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside diphosphate kinase-like domain
Functional Family Nucleoside diphosphate kinase

Enzyme Information

2.7.4.6
Nucleoside-diphosphate kinase.
based on mapping to UniProt P22887
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
-!- Many nucleoside diphosphates can act as acceptors. -!- Many ribo- and deoxyribonucleoside triphosphates can act as donors.

UniProtKB Entries (1)

P22887
NDKC_DICDI
Dictyostelium discoideum
Nucleoside diphosphate kinase, cytosolic

PDB Structure

PDB 1F6T
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for activation of alpha-boranophosphate nucleotide analogues targeting drug-resistant reverse transcriptase.
Meyer, P., Schneider, B., Sarfati, S., Deville-Bonne, D., Guerreiro, C., Boretto, J., Janin, J., Veron, M., Canard, B.
EMBO J.