CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family Non-specific serine/threonine protein kinase

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q13153
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q13153
PAK1_HUMAN
Homo sapiens
Serine/threonine-protein kinase PAK 1

PDB Structure

PDB 1F3M
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch.
Lei, M., Lu, W., Meng, W., Parrini, M.C., Eck, M.J., Mayer, B.J., Harrison, S.C.
Cell(Cambridge,Mass.)