CATH Classification

Domain Context

CATH Clusters

Superfamily Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase
Functional Family

Enzyme Information

5.4.99.61
Precorrin-8X methylmutase.
based on mapping to UniProt P21638
Precorrin-8X = hydrogenobyrinate.
-!- The enzyme catalyzes the the conversion of precorrin-8X to hydrogenobyrinate by methyl rearrangement, a step in the aerobic (late cobalt insertion) pathway of adenosylcobalamin biosynthesis. -!- The equivalent enzyme in the anaerobic pathway is EC 5.4.99.60. -!- Formerly EC 5.4.1.2.

UniProtKB Entries (1)

P21638
COBH_SINSX
Sinorhizobium sp.
Precorrin-8X methylmutase

PDB Structure

PDB 1F2V
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of precorrin-8x methyl mutase.
Shipman, L.W., Li, D., Roessner, C.A., Scott, A.I., Sacchettini, J.C.
Structure