CATH Classification

Domain Context

CATH Clusters

Superfamily Cytochrome P450
Functional Family Cytochrome P450 monooxygenase

Enzyme Information

1.7.1.14
Nitric oxide reductase (NAD(P)(+), nitrous oxide-forming).
based on mapping to UniProt P23295
Nitrous oxide + NAD(P)(+) + H(2)O = 2 nitric oxide + NAD(P)H.
-!- The enzyme from Fusarium oxysporum utilizes only NADH, but the isozyme from Trichosporon cutaneum utilizes both NADH and NADPH. -!- The electron transfer from NAD(P)H to heme occurs directly, not requiring flavin or other redox cofactors.

UniProtKB Entries (1)

P23295
NOR_FUSOX
Fusarium oxysporum
NADP nitrous oxide-forming nitric oxide reductase

PDB Structure

PDB 1F25
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Mutation effects of a conserved threonine (Thr243) of cytochrome P450nor on its structure and function.
Obayashi, E., Shimizu, H., Park, S.Y., Shoun, H., Shiro, Y.
J.Inorg.Biochem.