CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Casein kinase II subunit alpha

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P28523
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P28523
CSK2A_MAIZE
Zea mays
Casein kinase II subunit alpha

PDB Structure

PDB 1F0Q
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The replacement of ATP by the competitive inhibitor emodin induces conformational modifications in the catalytic site of protein kinase CK2.
Battistutta, R., Sarno, S., De Moliner, E., Papinutto, E., Zanotti, G., Pinna, L.A.
J.Biol.Chem.