CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.245 | Inosine-uridine Nucleoside N-ribohydrolase; Chain A |
|
3.90.245.10 | Ribonucleoside hydrolase-like |
Domain Context
CATH Clusters
| Superfamily | Ribonucleoside hydrolase-like |
| Functional Family | Inosine-uridine preferring nucleoside hydrolase |
Enzyme Information
| 3.2.2.2 |
Inosine nucleosidase.
based on mapping to UniProt P83851
Inosine + H(2)O = D-ribose + hypoxanthine.
|
| 3.2.2.3 |
Uridine nucleosidase.
based on mapping to UniProt P83851
Uridine + H(2)O = D-ribose + uracil.
|
UniProtKB Entries (1)
| P83851 |
IUNH_LEIMA
Leishmania major
Inosine-uridine preferring nucleoside hydrolase
|
PDB Structure
| PDB | 1EZR |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Nucleoside hydrolase from Leishmania major. Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-a crystal structure.
J.Biol.Chem.
|
