CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.150 | DNA polymerase; domain 1 |
|
1.10.150.20 | 5' to 3' exonuclease, C-terminal subdomain |
Domain Context
CATH Clusters
| Superfamily | 5' to 3' exonuclease, C-terminal subdomain |
| Functional Family | T5 flap endonuclease |
Enzyme Information
| 3.1.11.3 |
Exodeoxyribonuclease (lambda-induced).
based on mapping to UniProt P06229
Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 5'-phosphates.
-!- Preference for double-stranded DNA. -!- Does not attack single-strand breaks. -!- Similar enzymes: T4, T5 and T7 exonucleases, mammalian DNase IV. -!- Formerly EC 3.1.4.28.
|
| 3.1.11.- |
Exodeoxyribonucleases producing 5'-phosphomonoesters.
based on mapping to UniProt P06229
|
UniProtKB Entries (1)
| P06229 |
EXO5_BPT5
Escherichia virus T5
T5 flap endonuclease
|
PDB Structure
| PDB | 1EXN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease.
Nature
|