CATH Classification

Domain Context

CATH Clusters

Superfamily Leucine Dehydrogenase, chain A, domain 1
Functional Family

Enzyme Information

1.4.1.3
Glutamate dehydrogenase (NAD(P)(+)).
based on mapping to UniProt O74024
L-glutamate + H(2)O + NAD(P)(+) = 2-oxoglutarate + NH(3) + NAD(P)H.

UniProtKB Entries (1)

O74024
DHE3_THEPR
Thermococcus profundus
Glutamate dehydrogenase

PDB Structure

PDB 1EUZ
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Large-scale domain movements and hydration structure changes in the active-site cleft of unligated glutamate dehydrogenase from Thermococcus profundus studied by cryogenic X-ray crystal structure analysis and small-angle X-ray scattering.
Nakasako, M., Fujisawa, T., Adachi, S., Kudo, T., Higuchi, S.
Biochemistry