CATH Classification

Domain Context

CATH Clusters

Superfamily 2.40.128.20
Functional Family

Enzyme Information

1.7.6.1
Nitrite dismutase.
based on mapping to UniProt Q94734
3 nitrite + 2 H(+) = 2 nitric oxide + nitrate + H(2)O.
-!- The enzyme is one of the nitrophorins from the salivary gland of the blood-feeding insect Rhodnius prolixus. -!- Nitric oxide produced induces vasodilation after injection. -!- Nitrophorins 2 and 4 can also catalyze this reaction.

UniProtKB Entries (1)

Q94734
NP4_RHOPR
Rhodnius prolixus
Nitrophorin-4

PDB Structure

PDB 1ERX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Nitric oxide binding to nitrophorin 4 induces complete distal pocket burial.
Weichsel, A., Andersen, J.F., Roberts, S.A., Montfort, W.R.
Nat.Struct.Biol.