CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Structural polyprotein

Enzyme Information

3.4.21.90
Togavirin.
based on mapping to UniProt P05674
Autocatalytic release of the core protein from the N-terminus of the togavirus structural polyprotein by hydrolysis of a -Trp-|-Ser- bond.
-!- Once released, the core protein does not retain catalytic activity. -!- Belongs to peptidase family S3.

UniProtKB Entries (1)

P05674
POLS_EEVV8
Venezuelan equine encephalitis virus (strain TC-83)
Structural polyprotein

PDB Structure

PDB 1EP5
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
CRYSTAL STRUCTURE OF THE CONSERVED CORE DOMAIN OF VENEZUALAN EQUINE ENCEPHALITIS CAPSID PROTEIN
Watowich, S.J., Xu, Y., Lemon, A.P., Weaver, S.
To Be Published