CATH Classification

Domain Context

CATH Clusters

Superfamily HIT-like
Functional Family Fragile histidine triad

Enzyme Information

3.6.1.29
Bis(5'-adenosyl)-triphosphatase.
based on mapping to UniProt O76463
P(1)-P(3)-bis(5'-adenosyl) triphosphate + H(2)O = ADP + AMP.
3.5.-.-
Acting on carbon-nitrogen bonds, other than peptide bonds.
based on mapping to UniProt O76463

UniProtKB Entries (1)

O76463
NFT1_CAEEL
Caenorhabditis elegans
Nitrilase and fragile histidine triad fusion protein NitFhit

PDB Structure

PDB 1EMS
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the worm NitFhit Rosetta Stone protein reveals a Nit tetramer binding two Fhit dimers.
Pace, H.C., Hodawadekar, S.C., Draganescu, A., Huang, J., Bieganowski, P., Pekarsky, Y., Croce, C.M., Brenner, C.
Curr.Biol.