CATH Classification

Domain Context

CATH Clusters

Superfamily Aspartate/ornithine carbamoyltransferase
Functional Family Aspartate carbamoyltransferase 2

Enzyme Information

2.1.3.2
Aspartate carbamoyltransferase.
based on mapping to UniProt P0A786
Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate.

UniProtKB Entries (1)

P0A786
PYRB_ECOLI
Escherichia coli K-12
Aspartate carbamoyltransferase catalytic subunit

PDB Structure

PDB 1EKX
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Binding of bisubstrate analog promotes large structural changes in the unregulated catalytic trimer of aspartate transcarbamoylase: implications for allosteric regulation induced cell migration.
Endrizzi, J.A., Beernink, P.T., Alber, T., Schachman, H.K.
Proc.Natl.Acad.Sci.USA