CATH Classification

Domain Context

CATH Clusters

Superfamily Lumazine/riboflavin synthase
Functional Family 6,7-dimethyl-8-ribityllumazine synthase

Enzyme Information

2.5.1.78
6,7-dimethyl-8-ribityllumazine synthase.
based on mapping to UniProt P50861
1-deoxy-L-glycero-tetrulose 4-phosphate + 5-amino-6- (D-ribitylamino)uracil = 6,7-dimethyl-8-(D-ribityl)lumazine + 2 H(2)O + phosphate.
-!- Involved in riboflavin biosynthesis.

UniProtKB Entries (1)

P50861
RIB4_YEAST
Saccharomyces cerevisiae S288C
6,7-dimethyl-8-ribityllumazine synthase

PDB Structure

PDB 1EJB
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The atomic structure of pentameric lumazine synthase from Saccharomyces cerevisiae at 1.85 A resolution reveals the binding mode of a phosphonate intermediate analogue.
Meining, W., Mortl, S., Fischer, M., Cushman, M., Bacher, A., Ladenstein, R.
J.Mol.Biol.