CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1820 | alpha/beta hydrolase |
Domain Context
CATH Clusters
| Superfamily | alpha/beta hydrolase |
| Functional Family | palmitoyl-protein thioesterase 1 |
Enzyme Information
| 3.1.2.22 |
Palmitoyl-protein hydrolase.
based on mapping to UniProt P45478
Palmitoyl-[protein] + H(2)O = palmitate + [protein].
-!- Specific for long-chain thioesters of fatty acids. -!- Hydrolyzes fatty acids from S-acylated cysteine residues in proteins, palmitoyl cysteine and palmitoyl-CoA.
|
UniProtKB Entries (1)
| P45478 |
PPT1_BOVIN
Bos taurus
Palmitoyl-protein thioesterase 1
|
PDB Structure
| PDB | 1EI9 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The crystal structure of palmitoyl protein thioesterase 1 and the molecular basis of infantile neuronal ceroid lipofuscinosis.
Proc.Natl.Acad.Sci.USA
|