CATH Classification

Domain Context

CATH Clusters

Superfamily Rieske [2Fe-2S] iron-sulphur domain
Functional Family 3-phenylpropionate/cinnamic acid dioxygenase subunit alpha

Enzyme Information

1.14.12.12
Naphthalene 1,2-dioxygenase.
based on mapping to UniProt P0A110
Naphthalene + NADH + O(2) = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD(+).
-!- Comprises a multicomponent system, containing a reductase that is an iron-sulfur flavoprotein (FAD; EC 1.18.1.3), an iron-sulfur oxygenase, and ferredoxin.

UniProtKB Entries (1)

P0A110
NDOB_PSEPU
Pseudomonas putida
Naphthalene 1,2-dioxygenase system, large oxygenase component

PDB Structure

PDB 1EG9
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Substrate binding site of naphthalene 1,2-dioxygenase: functional implications of indole binding.
Carredano, E., Karlsson, A., Kauppi, B., Choudhury, D., Parales, R.E., Parales, J.V., Lee, K., Gibson, D.T., Eklund, H., Ramaswamy, S.
J.Mol.Biol.