CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.10 | Arc Repressor Mutant, subunit A |
|
1.10.10.60 | Homeodomain-like |
Domain Context
CATH Clusters
| Superfamily | Homeodomain-like |
| Functional Family |
Enzyme Information
| 2.7.7.6 |
DNA-directed RNA polymerase.
based on mapping to UniProt O26147
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized. -!- See also EC 2.7.7.19 and EC 2.7.7.48.
|
UniProtKB Entries (1)
| O26147 |
RPON_METTH
Methanothermobacter thermautotrophicus str. Delta H
DNA-directed RNA polymerase subunit N
|
PDB Structure
| PDB | 1EF4 |
| External Links | |
| Method | SOLUTION NMR |
| Organism | Escherichia |
| Primary Citation |
Zinc-bundle structure of the essential RNA polymerase subunit RPB10 from Methanobacterium thermoautotrophicum.
Proc.Natl.Acad.Sci.USA
|